COMPARISON OF NEXT-GENERATION SEQUENCING AND FLUORESCENCE IN SITU HYBRIDIZATION FOR DETECTION OF SEGMENTAL CHROMOSOMAL ABERRATIONS IN NEUROBLASTOMA

Comparison of Next-Generation Sequencing and Fluorescence In Situ Hybridization for Detection of Segmental Chromosomal Aberrations in Neuroblastoma

The aim of this study was to compare next-generation sequencing (NGS) with the traditional fluorescence in situ hybridization (FISH) for detecting segmental chromosomal aberrations (SCAs) such as 1p deletion, 11q deletion and 17q gain, which are well-known predictive markers for adverse outcome in neuroblastoma.The tumor tissue obtained from 35 pat

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Groundwater Depletion Estimated from GRACE: A Challenge of Sustainable Development in an Arid Region of Central Asia

Under climate change and increasing water demands, groundwater depletion has become regional and global threats for water security, which is an indispensable target to achieving sustainable developments of human society and ecosystems, especially in arid and semiarid regions where groundwater is a major water source.In this study, groundwater deple

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